Motif ID: HOX{A4,D4}.p2

Z-value: 0.635


Transcription factors associated with HOX{A4,D4}.p2:

Gene SymbolEntrez IDGene Name
HOXA4 3201 homeobox A4
HOXD4 3233 homeobox D4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA4chr7_-_271368760.391.3e-01Click!


Activity profile for motif HOX{A4,D4}.p2.

activity profile for motif HOX{A4,D4}.p2


Sorted Z-values histogram for motif HOX{A4,D4}.p2

Sorted Z-values for motif HOX{A4,D4}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A4,D4}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_74488910 2.366 ALB
albumin
chr4_+_74488947 2.192 ALB
albumin
chr4_+_74488835 2.126 NM_000477
ALB
albumin
chr4_+_74491272 2.016 ALB
albumin
chr17_-_61655915 1.281 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr22_+_19458378 1.080 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr14_-_53493198 0.995 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chrX_-_131401319 0.961 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr4_-_84254912 0.938 PLAC8
placenta-specific 8
chr7_-_149960612 0.907 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr22_+_21065134 0.902 LOC100290481
immunoglobulin lambda light chain-like
chr4_-_84254873 0.872 PLAC8
placenta-specific 8
chr17_-_59437782 0.862 NM_000873
ICAM2
intercellular adhesion molecule 2
chr8_-_17787342 0.861 FGL1
fibrinogen-like 1
chr4_-_84254932 0.845 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr7_-_87180499 0.808 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr22_+_21116283 0.806


chr11_+_22644732 0.702 NM_001143830
GAS2
growth arrest-specific 2
chr4_+_74520796 0.693 NM_001134
AFP
alpha-fetoprotein
chr10_-_116382089 0.688 ABLIM1
actin binding LIM protein 1
chr22_+_21065207 0.673 IGLJ3
immunoglobulin lambda joining 3
chr6_+_32713160 0.662 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr4_+_100714995 0.614 MTTP
microsomal triglyceride transfer protein
chr6_+_6533932 0.609 NM_004271
LY86
lymphocyte antigen 86
chr17_-_59451662 0.602 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr3_-_121883647 0.600 HGD
homogentisate 1,2-dioxygenase
chr6_+_12825022 0.591 PHACTR1
phosphatase and actin regulator 1
chr11_+_59979857 0.588 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr10_-_92671005 0.573 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr18_+_30810889 0.557 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_-_92144146 0.555 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chrX_-_76824726 0.553 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr1_-_149681265 0.542 NM_207171
POGZ
pogo transposable element with ZNF domain
chr20_-_33706532 0.542 RBM12
RNA binding motif protein 12
chr7_+_20621769 0.539 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr4_+_155707089 0.518 FGB
fibrinogen beta chain
chr1_-_149004852 0.510 CTSS
cathepsin S
chr14_-_37133927 0.505 FOXA1
forkhead box A1
chr17_-_35975227 0.498 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr17_+_50699965 0.498 HLF
hepatic leukemia factor
chr9_-_74735669 0.493 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr10_-_52315390 0.489 A1CF
APOBEC1 complementation factor
chr14_-_106249999 0.484 IGHA1
immunoglobulin heavy constant alpha 1
chr19_+_50100843 0.482 NM_000041
APOE
apolipoprotein E
chr14_+_63750611 0.476 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr1_+_148511806 0.475 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr2_+_54536780 0.468 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr10_-_52315436 0.462 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr14_-_94677807 0.459 NM_030621
DICER1
dicer 1, ribonuclease type III
chr17_+_38256710 0.455 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr14_-_37134191 0.447 NM_004496
FOXA1
forkhead box A1
chr6_+_32021793 0.443 CFB
complement factor B
chr4_-_186814852 0.432 SORBS2
sorbin and SH3 domain containing 2
chrM_+_1670 0.431 USP47
ubiquitin specific peptidase 47
chr6_+_32021831 0.430 CFB
complement factor B
chr3_+_134978615 0.424 TF
transferrin
chr22_+_21065202 0.423


chrX_+_37524190 0.420 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr19_-_7672978 0.410 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr1_-_205161821 0.410 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr7_-_1562272 0.409 NM_001097620
TMEM184A
transmembrane protein 184A
chr6_+_32021687 0.407 NM_001710
CFB
complement factor B
chr15_-_91078307 0.406 FAM174B
family with sequence similarity 174, member B
chr6_+_32021742 0.406 CFB
complement factor B
chr15_+_97990705 0.404 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr12_-_101835510 0.403 NM_000277
PAH
phenylalanine hydroxylase
chr1_+_66570363 0.402 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_+_63859114 0.401 NM_001177387
ATXN7
ataxin 7
chr1_-_167947301 0.401 NM_000655
SELL
selectin L
chr6_-_41811916 0.398 NM_001167827
TFEB
transcription factor EB
chr1_+_165564904 0.398 NM_001198783
POU2F1
POU class 2 homeobox 1
chr1_-_158883666 0.394 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr11_+_128069183 0.389 FLI1
Friend leukemia virus integration 1
chr6_+_64414389 0.389 NM_015153
PHF3
PHD finger protein 3
chr12_+_53177806 0.387 NCKAP1L
NCK-associated protein 1-like
chr2_+_33555182 0.385 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chrY_+_1415508 0.384 NM_002183
IL3RA
interleukin 3 receptor, alpha (low affinity)
chrX_+_1415508 0.384 NM_002183
IL3RA
interleukin 3 receptor, alpha (low affinity)
chr12_+_7039453 0.377


chr19_-_53081383 0.376 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr3_-_121884091 0.374 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr1_-_171441234 0.374 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr3_+_188222337 0.374 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr9_-_115877104 0.373 AMBP
alpha-1-microglobulin/bikunin precursor
chr15_-_35179185 0.365 MEIS2
Meis homeobox 2
chr14_-_22496196 0.363 HAUS4
HAUS augmin-like complex, subunit 4
chrX_+_37524250 0.362 CYBB
cytochrome b-245, beta polypeptide
chr6_-_32920689 0.355 NM_004159
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr19_-_53081326 0.355 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr22_-_36305883 0.355 NM_006498
LGALS2
lectin, galactoside-binding, soluble, 2
chr13_+_42034871 0.342 NM_033012
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr2_+_38746555 0.341 NM_138801
GALM
galactose mutarotase (aldose 1-epimerase)
chr1_-_108032645 0.340 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr8_-_17797127 0.333 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr1_-_171442937 0.333 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_+_53177789 0.332 NCKAP1L
NCK-associated protein 1-like
chrX_+_12795111 0.326 NM_016562
TLR7
toll-like receptor 7
chr10_-_64246129 0.324 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr14_+_38804226 0.324 NM_203354
CTAGE5
CTAGE family, member 5
chr12_+_53177758 0.316 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr19_-_53436088 0.316 NM_001184900
CARD8
caspase recruitment domain family, member 8
chr11_+_128069203 0.313 FLI1
Friend leukemia virus integration 1
chr1_+_165565006 0.312 POU2F1
POU class 2 homeobox 1
chr10_+_97461525 0.308 NM_001098175
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr3_-_172227461 0.304 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr6_+_32515596 0.302 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr2_-_20390601 0.302 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr10_+_28918672 0.301 WAC
WW domain containing adaptor with coiled-coil
chr9_+_79158164 0.301 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr12_-_120810899 0.297 NM_001171993
HPD
4-hydroxyphenylpyruvate dioxygenase
chr7_+_73262264 0.294 LAT2
linker for activation of T cells family, member 2
chr11_+_36572615 0.291 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr1_+_205328834 0.291 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr7_+_116447499 0.284 ST7
suppression of tumorigenicity 7
chr22_+_35639564 0.283 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_+_33554824 0.283 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_-_101831579 0.281 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chrM_+_13453 0.281


chr2_-_158008763 0.280 NM_004288
CYTIP
cytohesin 1 interacting protein
chr4_+_68107039 0.280 NM_012108
STAP1
signal transducing adaptor family member 1
chr9_-_122852356 0.279 NM_001735
C5
complement component 5
chr17_+_24394281 0.278 PIPOX
pipecolic acid oxidase
chr7_+_73262022 0.276 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr12_+_54760211 0.276 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr19_-_52427698 0.274 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr7_+_73262283 0.273 LAT2
linker for activation of T cells family, member 2
chr5_-_111121150 0.271 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr16_+_10430225 0.268 NM_024997
ATF7IP2
activating transcription factor 7 interacting protein 2
chr8_-_28403652 0.268 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr2_-_20375497 0.266 PUM2
pumilio homolog 2 (Drosophila)
chr20_-_23010786 0.260 CD93
CD93 molecule
chr2_-_165186603 0.259 NM_004490
GRB14
growth factor receptor-bound protein 14
chr12_-_9123126 0.257 A2M
alpha-2-macroglobulin
chr1_+_39694849 0.257 MACF1
microtubule-actin crosslinking factor 1
chr4_+_39874921 0.256 NM_004310
RHOH
ras homolog gene family, member H
chr8_+_75066117 0.253 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr10_-_69267774 0.252 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr2_-_133145539 0.252 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr10_-_92670764 0.252 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr7_+_116447527 0.250 ST7
suppression of tumorigenicity 7
chr1_+_190811479 0.249 NM_002922
RGS1
regulator of G-protein signaling 1
chr14_-_22354851 0.248 NM_001126105
NM_003982
SLC7A7

solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

chr3_-_11585264 0.246 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr6_+_88026338 0.244 ZNF292
zinc finger protein 292
chr2_+_127892489 0.244 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chrX_-_32083506 0.243 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr17_-_76883677 0.241 NM_001037984
NM_138570
SLC38A10

solute carrier family 38, member 10

chr12_+_12829807 0.237 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr12_+_53178834 0.235 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr11_+_46697345 0.235 F2
coagulation factor II (thrombin)
chr5_-_94250357 0.232 MCTP1
multiple C2 domains, transmembrane 1
chr20_-_45410033 0.232 ZMYND8
zinc finger, MYND-type containing 8
chr5_-_96175560 0.232 NM_001198541
ERAP1
endoplasmic reticulum aminopeptidase 1
chr10_-_101680645 0.231 DNMBP
dynamin binding protein
chr17_+_22982344 0.231 LGALS9
lectin, galactoside-binding, soluble, 9
chr20_+_31613800 0.230 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr13_-_74799898 0.230 TBC1D4
TBC1 domain family, member 4
chr1_+_63861474 0.230 NM_001172818
PGM1
phosphoglucomutase 1
chr11_+_128068982 0.228 NM_002017
FLI1
Friend leukemia virus integration 1
chr17_-_53849888 0.228 RNF43
ring finger protein 43
chr2_+_127892459 0.227 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr17_-_78599695 0.225 B3GNTL1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr12_+_99391870 0.223 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr16_+_28850760 0.223 NM_001178098
NM_001770
CD19

CD19 molecule

chr16_-_30032330 0.222 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr5_+_156628929 0.221 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr15_-_31147376 0.218 NM_001103184
FMN1
formin 1
chr14_+_69306019 0.215 SRSF5
serine/arginine-rich splicing factor 5
chr10_-_82039158 0.215 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr6_-_32892705 0.214 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr7_+_75382355 0.213 NM_000941
POR
P450 (cytochrome) oxidoreductase
chr14_-_22358752 0.212 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr16_+_31274030 0.212 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr6_+_32254108 0.212 NM_006913
RNF5
ring finger protein 5
chr2_-_188127294 0.211 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_101398429 0.211 IGF1
insulin-like growth factor 1 (somatomedin C)
chr12_-_51887318 0.211 ITGB7
integrin, beta 7
chr2_+_225973845 0.210 NM_020864
KIAA1486
KIAA1486
chr4_-_155731288 0.207 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr17_+_22982372 0.206 LGALS9
lectin, galactoside-binding, soluble, 9
chr3_-_47909001 0.205 MAP4
microtubule-associated protein 4
chr9_-_15500899 0.205 NM_001128217
NM_033222
PSIP1

PC4 and SFRS1 interacting protein 1

chr1_-_9040141 0.205 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_-_116021473 0.204 NM_001168325
NM_017899
TESC

tescalcin

chr16_+_29597829 0.203 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr22_+_21079355 0.203


chr5_+_180399830 0.203 NM_152547
BTNL9
butyrophilin-like 9
chr1_+_93317374 0.202 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chr2_+_86998248 0.201 NM_001024457
RGPD1
RANBP2-like and GRIP domain containing 1
chr13_-_47916803 0.201 NM_005767
LPAR6
lysophosphatidic acid receptor 6
chr17_-_36346240 0.201 KRT23
keratin 23 (histone deacetylase inducible)
chr7_+_75382408 0.198 POR
P450 (cytochrome) oxidoreductase
chr3_+_63928459 0.197 NM_001128149
ATXN7
ataxin 7
chr22_-_16070778 0.197 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr17_+_65009986 0.196 MAP2K6
mitogen-activated protein kinase kinase 6
chr9_-_115203220 0.195 ALAD
aminolevulinate dehydratase
chr1_+_54132447 0.194 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr17_+_38412267 0.194 NM_005533
IFI35
interferon-induced protein 35
chr9_-_115203371 0.193 ALAD
aminolevulinate dehydratase
chr4_+_140806536 0.192 MGST2
microsomal glutathione S-transferase 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.